DIGEORGE CRITICAL REGION GENE 1; DGCR1
Homo sapiens
False
TUP1 like enhancer of split protein 1
Homo sapiens, Mus musculus
False
TUPLE1
Mus musculus
False
primordial germ cells, chromatin assembly, DiGeorge Syndrome, heterochromatin, nucleosome, PML bodies, transcription factor, chromatin remodelling, APB, alt
Interphase
nuclear
putative localisation, no IF data
senescence
PML/ND10 bodies
as cells approach senescence
Interphase
ALT-associated PML body
68
98
WD40
WD1 domain, G-beta repeat
408
418
Poly_Gln
poly glutamine region
638
641
Poly_Lys
poly lysine region
803
806
Poly_Val
poly valine region
GO:0006336
DNA replication-independent nucleosome assembly
GO:0006325
establishment and/or maintenance of chromatin architecture
GO:0006357
regulation of transcription from Pol II promoter
GO:0006338
chromatin remodeling
GO:0003702
RNA polymerase II transcription factor activity
Gastrulation Defects and Patterning Abnormalities of Mesoendodermal Derivatives
In situ
Ubiquitous, high expression in cranial neural folds, subregions of pharyngeal arches 1and 2, circumpharyngeal neural crest and limb buds
In situ
Chicken HIRA, expressed in the developing neural plate, the neural tube, neural crest and the mesenchyme of the head and branchial arch structures
Northern
Two alternative spliced forms, long form is predominate with short form more abundant in the heart. Most abundant expression in heart, skeletal muscle, pancreas and kidney
accumulate in nuclei of PGCs during reprogramming
Hir1p
Saccharomyces cerevisiae
Hir2p
Saccharomyces cerevisiae