nuclear receptor, heterodimer, ligand binding domain holi, zinc finger C4
GO:0050874
organismal physiological process
GO:0006357
regulation of transcription from Pol II promoter
GO:0003706
ligand-regulated transcription factor activity
Cholesterol and bile acid metabolism are impaired. k.o mice have no ability to respond normally to dietary cholesterol and are unable to tolerate any amount of cholesterol in excess of that which they synthesize de novo
Northern
strong expression of a 1.9-kb transcript in metabolic organs such as liver, kidney, and intestine
2002-06-03 17:18:08
2007-07-27 12:26:03