Names
X
Name
Species
Main
ICBP90 
 
False 
Np95 
Homo sapiens, Mus musculus 
True 
UHRF1 
Mus musculus 
False 
RNF106 
 
false 
Keywords
X
methyl-lysine binding, heterochromatin, histone ubiquitination, chromatin binding, ubiquitin, ubiquitin ligase, methylated DNA binding, DNA methylation, H3K9me3 binding, PHD finger, RING finger, tudor, SRA, histone ubiquitination
Location
X
Location
Species
17DE1 
Mus musculus 
19p13.3 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
S - interphase 
replication foci 
co-localisation with pcna 
PubMed:10984098
G2 
nuclear dots 
 
PubMed:11161719
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
91 
7.66 
 
 
806 
OMIM:607990
Entrez Protein:NP_037414
Uniprot:Q96T88
88.3 
8.63 
95 
 
782 
Entrez Protein:AAK55743
Uniprot:Q9Z1H6
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0006338 
chromatin remodeling 
PubMed:14993289
GO:0006325 
establishment and/or maintenance of chromatin architecture 
PubMed:17182844
GO:0000084 
S phase of mitotic cell cycle 
PubMed:12058012
GO:0010216 
maintenance of DNA methylation 
pubmed:19798101
pubmed:23463006
pubmed:24013172
pubmed:24253042
pubmed:24368767
pubmed:28803780
GO:0070828 
heterochromatin organization 
pubmed:18508923
pubmed:17994007
pubmed:17673620
GO:0016574 
histone ubiquitination 
pubmed:24013172
pubmed:27595565
GO:0031056 
regulation of histone modification 
pubmed:29968706
Molecular Function
X
GO ID
Term
Links
GO:0004842 
ubiquitin-protein ligase activity 
PubMed:14993289
pubmed:24013172
pubmed:27595565
GO:0035064 
methylated histone residue binding 
pubmed:17967883
pubmed:20026581
pubmed:21489993
pubmed:29656054
GO:0010385 
double-stranded methylated DNA binding 
pubmed:18772891
pubmed:18772889
pubmed:17994007
pubmed:23434322
GO:0042393 
histone binding 
pubmed: 22096602
pubmed:24813945
GO:0044729 
hemi-methylated DNA-binding 
pubmed:27595565
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Immunofluorescence 
S phase sepcific in normal cells 
PubMed:12058012
PubMed:9880673
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2002-06-11 09:10:41 
2007-07-25 16:10:03