Names
Name
Species
Main
PR-Set7 
Homo sapiens 
True 
SET07 
 
False 
SET8 
 
False 
Setd8 
 
false 
Keywords
set domain, transmembrane, chromosome condensation, histone methylation, mitotic chromosomes, dna damage response, H4K20 methylation, DNA replication, DNA replication licensing, EMT, senescence
Location
Subcellular Localisation
Stage
Description
Details
Links
Mitosis 
chromosomal 
parallels increased H4 K20 methylation at mitosis 
S phase 
replication origins 
 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
27 
transmembrane 
 
29 
32 
NLS 
 
161 
164 
NLS 
 
208 
214 
NLS 
 
220 
236 
NLS BP 
 
257 
384 
SET 
 
Biological Process
GO ID
Term
Links
GOIDHERE 
DNA damage response, signal transduction by p53 class mediator 
GO:0005657 
replication fork 
GO:0000084 
S phase of mitotic cell cycle 
GO:0007049 
cell cycle 
GO:0009790 
embryonic development 
GO:0030261 
chromosome condensation 
GO:0006275 
regulation of DNA replication 
GO:0016481 
negative regulation of transcription 
GO:0016481 
negative regulation of transcription 
GOIDHERE 
initiation of DNA replication 
GOIDHERE 
initiation of DNA replication 
GOIDHERE 
initiation of DNA replication 
GO:0001837 
epithelial to mesenchymal transition 
GO:2000773 
negative regulation of cellular senescence 
Molecular Function
GO ID
Term
Links
GO:0042799 
histone lysine N-methyltransferase activity (H4-K20 specific) 
GOIDHERE 
lysine N-methyltransferase 
Other Function
Function
Links
Expression
Experiment
Detail
Links
 
regulated during cell cycle 
 
degraded during s phase & DNA damage 
Related Genes
Name
Species
Links
PR-Set7 
Drosophila melanogaster 
History
Created On
Last Changed
2002-07-03 14:23:41 
2005-08-18 13:17:03