Names
X
Name
Species
Main
H-L(3)MBT 
 
False 
KIAA0681 
 
False 
L3MBT 
Homo sapiens 
True 
L3MBTL1 
 
False 
L3MBTR 
 
False 
Lethal(3)malignant brain tumor protein homolog 
 
False 
Keywords
X
mbt, chromatin binding, histone demethylation, mitotic chromosomes, zinc finger C2HC, E2F6 complex, methyl-lysine binding, chromatin compaction, genome stability
Location
X
Location
Species
20q12 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Mitosis 
chromosomal 
 
PubMed:99373015
Interphase 
nuclear 
 
PubMed:99373015
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
85.9 
5.7 
 
 
772 
Entrez Protein:NP_056293
Uniprot:Q9Y468
Annotation
X
Start
End
Domain
Description
206 
306 
mbt repeat 
 
314 
413 
mbt repeat 
 
422 
517 
mbt repeat 
 
550 
581 
C2HC Zn finger 
 
Biological Process
X
GO ID
Term
Links
GO:0006325 
establishment and/or maintenance of chromatin architecture 
PubMed:17540172
GO:0000122 
negative regulation of transcription from Pol II promoter 
PubMed:21999559
GO:0048863 
stem cell differentiation 
pubmed:21341991
GOIDHERE 
genome stability 
pubmed: 21149733
Molecular Function
X
GO ID
Term
Links
GO:0035064 
methylated histone residue binding 
PubMed:17540172
pubmed:18026117
pubmed:18042461
pubmed:18408754
Other Function
X
Function
Links
normal development in knockout mice 
pubmed: 20592034
Expression
X
Experiment
Detail
Links
 
higherst in brain 
pubmed: 20592034
Related Genes
X
Name
Species
Links
l(3)mbt 
Drosophila melanogaster 
PubMed:99373015
History
X
Created On
Last Changed
2002-11-25 16:08:11 
2007-10-05 17:45:35