Names
Name
Species
Main
FBXL10 
 
False 
JEMMA 
Homo sapiens 
True 
PCCX2 
 
False 
JHDM1B 
Homo sapiens 
false 
Kdm2b 
 
false 
CXXC2 
 
false 
NDY 
 
false 
Keywords
BCOR complex, rRNA transcription, nucleolus, jumonji domain, f box, histone demethylation, leucine_rich repeat, zinc finger CXXC, PHD finger, H3K4 demethylation, H3K36 demethylation, histone demethylase, neural tube, H2A ubiquitination, stem cell, pluripotency, DNA demethylation, DNA repair, ubiquitin ligase complex
Location
Location
Species
12q24.31 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
nucleolus 
 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
14 
21 
NLS 
 
178 
346 
JmjC 
 
224 
230 
NLS 
 
459 
462 
NLS 
 
605 
651 
CXXC Zn finger 
 
607 
610 
NLS 
 
661 
723 
PHD finger 
 
774 
780 
NLS 
 
792 
818 
NLS BP 
 
866 
870 
NLS 
 
885 
891 
NLS 
 
927 
933 
NLS 
 
936 
940 
NLS 
 
1065 
1105 
fbox 
 
1148 
1170 
LRR 
 
1172 
1197 
LRR 
 
1212 
1236 
LRR 
 
1237 
1262 
LRR 
 
1267 
1291 
LRR 
 
1292 
1317 
LRR 
 
Biological Process
GO ID
Term
Links
GO:0016577 
histone demethylation 
GO:0016479 
negative regulation of transcription from RNA polymerase I promoter 
GO:0003750 
cell cycle regulator 
GO:0007420 
brain development 
GO:0001843 
neural tube closure 
GO:0033182 
regulation of histone ubiquitination 
GO:0006340 
negative regulation of transcription of homeotic gene (Polycomb group) 
GO:0019827 
stem cell maintenance 
GO:0044030 
regulation of DNA methylation 
GO:0006282 
regulation of DNA repair 
Molecular Function
GO ID
Term
Links
GO:0032453 
histone demethylase activity (H3-K4 specific) 
GO:0070544 
histone H3-K36 demethylation 
GO:0051213 
dioxygenase activity 
GO:0000151 
ubiquitin ligase complex 
Other Function
Function
Links
embryonic lethal 
Expression
Related Genes
Name
Species
Links
T26A5.5 
Caenorhabditis elegans 
History
Created On
Last Changed
2003-02-05 09:47:29 
2006-02-16 09:38:27