Names
Name
Species
Main
EXO1 
Homo sapiens 
True 
exonuclease 1 
 
False 
Hex1 
 
False 
Keywords
homologous recombination, DNA repair, exonuclease, ds break repair, meiosis, telomere, structure-specific nuclease, end resection
Location
Location
Species
1q42-q43 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
99 
XPGN 
 
138 
208 
XPGI 
 
212 
245 
helix hairpin helix (HHH) 
 
290 
296 
NLS 
 
418 
421 
NLS 
 
775 
778 
NLS 
 
Biological Process
GO ID
Term
Links
GO:0007127 
meiosis I 
GO:0000724 
double-strand break repair via homologous recombination 
GO:0000723 
telomere maintenance 
Molecular Function
GO ID
Term
Links
GO:0008409 
5.-3. exonuclease activity 
Other Function
Function
Links
Expression
Experiment
Detail
Links
Northern 
high expression of an approximately 4.0-kb transcript in fetal liver and adult bone marrow. ow levels in other tissues 
Related Genes
Name
Species
Links
EXO1 
Saccharomyces cerevisiae 
History