Names
X
Name
Species
Main
BIG-3 
 
False 
WDR5 
Homo sapiens, Mus musculus 
True 
Keywords
X
ubiquitination, midbody, methyl-lysine binding, atac complex, wd40, histone acetylation, histone methylase complex, MLL, H4K16 acetylation, NSL complex, WRAD complex, compass complex, genetic disease, congenital heart disease
Location
X
Location
Species
9q34 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
nucleolus 
 
PubMed:15635413
cytokinesis 
cleavage midbody 
 
pubmed:25666610
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
36.6 
8.54 
 
 
334 
Entrez Protein:NP_060058
PubMed:16600877
Uniprot:Q9UGP9
PubMed:23665959
Annotation
X
Start
End
Domain
Description
34 
73 
WD40 
 
76 
115 
WD40 
 
118 
157 
WD40 
 
160 
199 
WD40 
 
202 
242 
WD40 
 
245 
287 
WD40 
 
290 
331 
WD40 
 
Biological Process
X
GO ID
Term
Links
GO:0007623 
circadian rhythm 
PubMed:15860628
GO:0016571 
histone methylation 
PubMed:15960974
PubMed:14992727
PubMed:12670868
pubmed:21106533
GO:0016568 
chromatin modification 
pubmed:18838386
GO:0006357 
regulation of transcription from RNA polymerase II promoter 
pubmed:17355966
GO:0016573 
histone acetylation 
pubmed:20018852
Molecular Function
X
GO ID
Term
Links
GO:0003682 
chromatin binding 
PubMed:15960974
PubMed:16946699
PubMed:16829960
PubMed:16600877
GO:0031464 
Cul4A-RING ubiquitin ligase complex 
pubmed:17041588
GO:0000123 
histone acetyltransferase complex 
pubmed:18838386
pubmed:20018852
GO:0035097 
histone methyltransferase complex 
pubmed:17355966
pubmed:18840606
GO:0048188 
Set1C/COMPASS complex 
pubmed:17355966
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
swd3 
Saccharomyces cerevisiae 
PubMed:12670868
History
X
Created On
Last Changed
2003-04-07 12:52:07 
2005-10-14 15:56:36