Names
Keywords
intellectual disability, CTD kinase, microcephaly, genetic disease, splicing speckles, serine threonine kinase, alternative splicing, wnt signalling, histone phosphorylation, autism
Location
Location
Species
21q22.1 
Homo sapiens 
16 
Mus musculus 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
splicing speckles 
 
Interphase 
nuclear and cytoplasmic 
 
Annotation
Start
End
Domain
Description
114 
133 
NLS BP 
 
159 
479 
S_TKc 
 
389 
395 
NLS 
 
Biological Process
GO ID
Term
Links
GOIDHERE 
alternative mRNA splicing, via spliceosome 
GO:0006468 
protein phosphorylation 
GO:0035412 
regulation of catenin import into nucleus 
GO:0016572 
histone phosphorylation 
GO:0045944 
positive regulation of transcription from RNA polymerase II promoter 
GO:0030217 
T cell differentiation 
GO:0070816 
phosphorylation of RNA polymerase II C-terminal domain 
Molecular Function
GO ID
Term
Links
GO:0004674 
protein serine/threonine kinase activity 
GO:0035173 
histone kinase activity 
GO:0008353 
RNA polymerase II carboxy-terminal domain kinase activity 
Other Function
Function
Links
haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology 
Expression
Experiment
Detail
Links
Northern 
ubiquitous 
 
specific neurons 
Related Genes
Name
Species
Links
mnb 
Drosophila melanogaster 
History
Created On
Last Changed
2003-06-13 16:32:36 
2003-06-13 16:50:18