SH2, arginine methylated, tyrosine phosphorylated, transcription factor, genetic disease, serine phosphorylated, immunodeficiency, signal transduction, transcription activation
2q32.2-q32.3
Homo sapiens
Interphase
nuclear-cytoplasmic shuttling
depends on JAK1
Interphase
nuclear
upon tyrosine phosphorylation
GO:0006357
regulation of transcription from Pol II promoter
GO:0003701
RNA polymerase I transcription factor activity
compromised innate immunity to viral disease
Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation
2003-08-22 09:21:34
2003-08-22 10:19:56