Names
X
Name
Species
Main
E2F-1 
 
False 
E2F1 
Homo sapiens, Mus musculus 
True 
PBR3 
 
False 
RBAP-1 
 
False 
RBBP3 
 
False 
Keywords
X
8653789, E2F, heterodimer, homodimer, house mouse, human, transcription factor, tumour suppressor
Location
X
Location
Species
2 
Mus musculus 
20q11.2 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
46.9 
4.79 
 
 
437 
Entrez Protein:Q01094
OMIM:189971
Uniprot:Q01094
 
 
 
 
430 
Entrez Protein:Q61501
Uniprot:Q61501
Annotation
X
Start
End
Domain
Description
1 
31 
signal peptide 
 
86 
93 
NLS 
 
123 
338 
E2F_TDP 
 
Biological Process
X
GO ID
Term
Links
GO:0006915 
apoptosis 
PubMed:11034215
GO:0000122 
negative regulation of transcription from Pol II promoter 
PubMed:10199402
GO:0000080 
G1 phase of mitotic cell cycle 
PubMed:10199402
GO:0006357 
regulation of transcription from Pol II promoter 
PubMed:8618861
Molecular Function
X
GO ID
Term
Links
GO:0003677 
DNA binding 
PubMed:1638634
PubMed:7784053
GO:0008181 
tumor suppressor 
PubMed: 8653789
Other Function
X
Function
Links
skeletal muscle regeneration 
PubMed:15304485
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
History
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