Names
X
Name
Species
Main
KIAA0052 
Homo sapiens 
True 
MTR4 
 
False 
Dob1 
 
false 
SKIV2L2 
 
false 
Keywords
X
ski complex, helicase, DEAD box, nuclear mRNA splicing via spliceosome, RNA degradation, nucleolus, ribosome biogenesis, rRNA processing, exosome, TRAMP complex, NEXT complex
Location
X
Location
Species
5q11.2 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
nucleolus 
 
PubMed:15635413
pubmed: 16782053
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
118 
6.24 
 
 
 
Entrez Protein:NP_056175
Uniprot:P42285
Annotation
X
Start
End
Domain
Description
78 
81 
NLS 
 
136 
319 
DEXDc 
 
439 
528 
Helicase_C 
 
820 
850 
coiled-coil 
 
824 
840 
NLS BP 
 
840 
856 
NLS BP 
 
Biological Process
X
GO ID
Term
Links
GO:0000398 
nuclear mRNA splicing, via spliceosome 
PubMed:12176931
GO:0050779 
RNA destabilization 
pubmed:11719186
pubmed:25175027
GO:0042254 
ribosome biogenesis 
pubmed: 16782053
GO:0006364 
rRNA processing 
pubmed:17412707
GO:0034984 
cellular response to DNA damage stimulus 
pubmed:28431250
Molecular Function
X
GO ID
Term
Links
GO:0000178 
exosome (RNase complex) 
pubmed:11719186
GO:0004386 
helicase activity 
pubmed: 19707589
GO:0031499 
TRAMP complex 
pubmed:25175027
Other Function
X
Function
Links
Expression
+
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2004-11-04 11:32:41 
2006-07-13 16:22:34