Names
X
Name
Species
Main
Lem2 
Homo sapiens, Mus musculus 
True 
Lemd2 
 
False 
NET25 
 
False 
Keywords
X
lem domain, nuclear membrane, transmembrane, ERK signalling, inm, genetic disease, ESCRT
Location
X
Location
Species
6p21.31 
Homo sapiens 
17A3.3 
Mus musculus 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
inner nuclear membrane 
 
PubMed:16339967
Interphase 
nuclear periphery 
 
PubMed Central:17062158
pubmed:20091084
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
57.5 
9.18 
 
 
511 
Entrez Protein:NP_666187
Uniprot:Q6DVA0
PubMed:30905398
PubMed:31061923
pubmed:36377660
pubmed:37867468
 
 
 
 
503 
Entrez Protein:NP_851853
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0006998 
nuclear membrane organization and biogenesis 
PubMed:17097643
pubmed:28242692
pubmed:32601372
GO:0045445 
myoblast differentiation 
pubmed:19720741
GO:0070372 
negative regulation of ERK1 and ERK2 cascade 
pubmed:19720741
GO:0000815 
ESCRT III complex 
pubmed:31147383
GOIDHERE 
nuclear membrane repair 
pubmed:31147383
GO:0031468 
nuclear envelope reassembly 
pubmed:32494070
Molecular Function
X
GO ID
Term
Links
Other Function
X
Function
Links
embryonic lethal 
pubmed:25790465
Expression
X
Experiment
Detail
Links
 
upregulated during myogenesis 
pubmed:17062158
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2005-09-30 12:45:29 
2007-06-20 16:17:12