Names
Name
Species
Main
NET47 
Homo sapiens 
True 
TM7SF2 
 
false 
ANG1 
 
false 
DHCR14A 
 
false 
delta(14)-sterol reductase 
 
false 
C14SR 
 
false 
erg24 
 
false 
Keywords
nuclear periphery, transmembrane, cholesterol biosynthesis, sterol reductase, ER, transcription repression
Location
Location
Species
11q13 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
nuclear periphery 
 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
13 
35 
transmembrane 
 
62 
81 
transmembrane 
 
102 
124 
transmembrane 
 
129 
148 
transmembrane 
 
255 
277 
transmembrane 
 
287 
304 
transmembrane 
 
355 
377 
transmembrane 
 
Biological Process
GO ID
Term
Links
GO:0006695 
cholesterol biosynthetic process 
GO:0006998 
nuclear envelope organization 
GO:0005783 
endoplasmic reticulum 
GO:0005783 
endoplasmic reticulum 
GO:0000122 
negative regulation of transcription from RNA polymerase II promoter 
Molecular Function
GO ID
Term
Links
GO:0050613 
delta14-sterol reductase activity 
Other Function
Function
Links
knockout has no defect in cholesterol biosynthesis 
Expression
Experiment
Detail
Links
 
regulated by sterol levels 
 
high in liver 
Related Genes
Name
Species
Links
History
Created On
Last Changed
2010-05-11 15:01:53 
0000-00-00 00:00:00