Names
Name
Species
Main
IFI16 
Homo sapiens 
True 
IFNGIP1 
 
false 
PYHIN2 
 
false 
Keywords
innate immunity, DNA binding, nucleolus, transcription repression, p53 binding, senescence, senescence-associated secretory phenotype, pyrin, PAAD domain, HIN200, ob fold, viral restriction, brca1 complex, heterochromatin
Location
Location
Species
1q22 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
nuclear 
 
Interphase 
nucleolus 
 
Interphase 
nuclear & cytoplasmic 
translocates to cytoplasm upon activation 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
84 
PAAD_DAPIN 
 
145 
314 
HIN 
 
518 
685 
HIN 
 
Biological Process
GO ID
Term
Links
GO:0000122 
negative regulation of transcription from RNA polymerase II promoter 
GO:0090398 
cellular senescence 
GOIDHERE 
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 
GO:0070869 
heterochromatin assembly involved in chromatin silencing 
Molecular Function
GO ID
Term
Links
GO:0002039 
p53 binding 
GO:0006330 
single-stranded DNA binding 
GO:0003800 
antiviral response protein activity 
GO:0061702 
inflammasome complex 
GO:0043566 
structure-specific DNA binding 
Other Function
Function
Links
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
History
Created On
Last Changed
2013-08-01 14:03:41 
0000-00-00 00:00:00