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Names
X
Name
Species
Main
F9/12C4
Mus musculus
False
MCM6
Homo sapiens, Mus musculus
True
Mis5
Schizosaccharomyces pombe
False
mMIS5
Mus musculus
False
RLF-M
Homo sapiens
False
Keywords
X
AAA, chromatin associated, DNA replication licensing, gene trap, helicase, CMG complex, MCM family, nuclear foci, replication origin
Location
X
Location
Species
MMU1
Mus musculus
HSA2q21
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nuclear dots
gene trap in multiple foci, not all cells - probably cell cycle
PubMed:11555636
PubMed:9077461
Interphase
chromatin
loaded in late mitosis
PubMed:11046155
Interphase
replication origins
PubMed:10834843
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
92.9
5.32
105
821
PubMed:11555636
PubMed:9077461
Entrez Nucleotide:D86726
Uniprot:P97311
92.9
5.29
821
Entrez Nucleotide:D84557
Uniprot:Q14566
Annotation
X
Start
End
Domain
Description
1
773
gene trap insertion
119
657
MCM
1
773
gene trap insertion
1
821
full length
119
657
MCM
388
540
AAA ATPase
Biological Process
X
GO ID
Term
Links
GO:0006268
DNA unwinding
PubMed:10834843
GO:0006267
pre-replicative complex formation and maintenance
PubMed:10834843
GO:0006275
regulation of DNA replication
PubMed:9077461
Molecular Function
X
GO ID
Term
Links
GO:0003682
chromatin binding
GO:0003678
DNA helicase activity
PubMed Central:11136247
GO:0003687
DNA replication factor
GO:0003688
DNA replication origin binding
PubMed:10834843
Other Function
X
Function
Links
Expression
+
Related Genes
X
Name
Species
Links
MCM6
Saccharomyces cerevisiae
Entrez Protein:S64219
Uniprot:P53091
MCM6
Xenopus laevis
Entrez Protein:T47222
History
X
Created On
Last Changed
2000-11-02 10:28:23
2004-10-14 13:01:57