acute leukemia, acute lymphoblastic leukemia ALL, AML, bromodomain, fycn, histone methylase, homeotic gene regulation, leukaemia, leukaemia_associated translocation, lymphoma_associated translocation, mitotic chromosomes, segment identity, Trithorax group TrxG, zinc finger CXXC, set domain, AT-hook, H3K4me3 binding, H3K4 methylation, MLL1/2 complex, genetic disease, transcription activation, transcription repression, proline isomerisation, genetic disease, Wiedemann-Steiner syndrome, CdLS, FY-rich domain
Interphase
PcG bodies
In foci with Bmi, antagonist to Bmi
1
170
gene trap insertion
1400
1600
leukaemia breakpoint cluster
GO:0016571
histone methylation
GO:0000122
negative regulation of transcription from Pol II promoter
GO:0007379
segment specification
GO:0006344
maintenance of chromatin silencing
GO:0042800
histone lysine N-methyltransferase activity (H3-K4 specific)
GO:0035064
methylated histone residue binding
Set1
Saccharomyces cerevisiae
trithorax
Drosophila melanogaster
2001-01-05 17:37:50
2005-08-18 13:20:36