N-CoR
Homo sapiens, Mus musculus
False
AML, chromatin remodelling, gene trap, histone deacetylase complex, nuclear foci, nuclear receptor interacting, repression complex, SANT, NCor complex
Interphase
diffuse
gene trap distribution
Interphase
repair foci
wt in foci with HDACs and SMRT
GO:0006338
chromatin remodeling
GO:0000122
negative regulation of transcription from Pol II promoter
GO:0016575
histone deacetylation
GO:0003706
ligand-regulated transcription factor activity
controls differentiation of neural stem cells into astrocytes. embryonic cortical progenitorsdisplay impaired self-renewal and spontaneous differentiation into astroglia-like cells.
Northern
TRH and NCoR mRNA expression inversely correlated during postnatal development
and as a function of thyroid status