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Names
X
Name
Species
Main
Chek1
Homo sapiens
False
Chk1
Homo sapiens, Mus musculus, Schizosaccharomyces pombe
False
ESKN86
True
Keywords
+
Location
+
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nuclear speckles
PubMed:11555636
PubMed:9278511
meiosis
synaptonemal complex
PubMed:9382850
Interphase
chromatin
PubMed:12676962
PubMed:16360315
Interphase
centrosome
PubMed:15311285
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
54.4
8.5
476
PubMed:10761933
PubMed:9278511
OMIM:603078
Entrez Nucleotide:AF016582
Uniprot:O14757
54.4
8.66
476
PubMed:10859163
PubMed:10859164
PubMed:11555636
PubMed:9278511
Uniprot:O35280
Annotation
X
Start
End
Domain
Description
1
420
gene trap insertion
1
476
full length
9
265
S_TKc
176
182
NLS
257
263
NLS
274
277
NLS
345
phosphorylated serine
In response to uv, ir and hu by Atr
Biological Process
X
GO ID
Term
Links
GO:0000077
DNA damage checkpoint
PubMed:15261141
GO:0000076
DNA replication checkpoint
PubMed:11535615
PubMed:15261141
GO:0000724
double-strand break repair via homologous recombination
PubMed:15665856
GO:0006974
response to DNA damage stimulus
PubMed:11158294
PubMed:10859164
PubMed:12399544
PubMed:9278511
GO:0000086
G2/M transition of mitotic cell cycle
PubMed:15311285
GO:0007059
chromosome segregation
pubmed:19289837
GO:0000910
cytokinesis
pubmed:19289837
Molecular Function
X
GO ID
Term
Links
GO:0004674
protein serine/threonine kinase activity
PubMed:10761933
PubMed:12399544
Other Function
X
Function
Links
Expression
+
Related Genes
X
Name
Species
Links
Chk1
Schizosaccharomyces pombe
Uniprot:P34208
Chk1
Caenorhabditis elegans
grapes (grp)
Drosophila melanogaster
Uniprot:O61661
Cds1
Schizosaccharomyces pombe
Chk1
Saccharomyces cerevisiae
History
X
Created On
Last Changed
2001-02-09 14:35:17
2005-05-05 16:22:16