Names
X
Name
Species
Main
Sp140 
Homo sapiens, Mus musculus 
True 
Keywords
X
bromodomain, PML bodies, sand, PHD finger, H3K27me3 binding, macrophage, innate immunity
Location
X
Location
Species
2 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
PML/ND10 bodies 
 
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
85.9 
5.53 
 
 
753 
Entrez Protein:NP_009168
PubMed: 97067175
Annotation
X
Start
End
Domain
Description
1 
753 
full length 
 
380 
401 
NLS BP 
 
421 
437 
NLS BP 
 
462 
465 
NLS 
 
474 
547 
SAND 
 
488 
491 
NLS 
 
550 
559 
NLS 
 
578 
620 
PHD finger 
 
642 
745 
Bromo 
 
Biological Process
X
GO ID
Term
Links
GO:0042116 
macrophage activation 
pubmed:28783698
pubmed:35986286
pubmed:35952671
GO:0060339 
negative regulation of type I interferon-mediated signaling pathway 
pubmed:34151776
pubmed:35986286
GO:0045087 
innate immune response 
pubmed:34151776
Molecular Function
X
GO ID
Term
Links
GO:0035064 
methylated histone binding 
pubmed:28783698
GO:0061628 
H3K27me3 modified histone binding 
pubmed:28783698
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
 
immune cells 
pubmed:8910577
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2001-03-26 12:24:40 
2002-06-06 17:47:24