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Names
X
Name
Species
Main
Sin3
Homo sapiens, Mus musculus
True
Sin3a
False
Keywords
X
centromere protein, histone deacetylase complex, neocentromere, PAH, replication origin, repression complex, genetic disease, Witteveen-Kolk syndrome
Location
X
Location
Species
15q23
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
G1
replication origins
earliest origins of primary cells, targetting via RBBP1
PubMed:11283269
S - interphase
replication origins
earliest origins of primary cells
PubMed:11283269
G1
perinucleolar
earliest origins of primary cells
PubMed:11283269
S - interphase
perinucleolar
earliest origins of primary cells
PubMed:11283269
metaphase - mitosis
centromere
active centromeres and neocentromeres
PubMed:14519686
metaphase - mitosis
kinetochore
PubMed:14519686
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
146.2
6.84
1282
PubMed:10551834
PubMed:11106735
Entrez Nucleotide:L36831
PubMed:36758531
1273
Entrez Protein:NP_056292
Annotation
X
Start
End
Domain
Description
141
187
pah
322
381
pah
428
444
NLS BP
478
524
pah
686
702
NLS BP
Biological Process
X
GO ID
Term
Links
GO:0006325
establishment and/or maintenance of chromatin architecture
PubMed:11238380
GO:0000122
negative regulation of transcription from Pol II promoter
PubMed:10734093
GO:0006342
chromatin silencing
pubmed:18995834
Molecular Function
X
GO ID
Term
Links
Other Function
X
Function
Links
essential
PubMed:16055712
Expression
+
Related Genes
X
Name
Species
Links
Sin3
Xenopus laevis
PubMed:10454532
Entrez Nucleotide:AF154112
Sin3
Saccharomyces cerevisiae
PubMed:10655212
PubMed:10388812
PubMed:9234741
Sin3
Caenorhabditis elegans
PubMed:10904264
dSIN3
Drosophila melanogaster
PubMed:9799435
History
X
Created On
Last Changed
2001-04-05 13:34:19
2005-09-07 09:10:03