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Names
X
Name
Species
Main
lamin A/C
Gallus gallus, Homo sapiens, Mus musculus, Rattus norvegicus
True
Keywords
X
farnesylation, intermediary filament, replication origin, nuclear periphery
Location
X
Location
Species
3
Mus musculus
1q21.2-q21.3
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nuclear periphery
nuclear lamina
PubMed:15596010
G1
replication origins
earliest replication origins of primary cells
PubMed:11090133
PubMed:7738105
S - interphase
replication origins
earliest replication origins of primary cells
PubMed:11090133
G1
perinucleolar
earliest replication origins of primary cells are often perinucleolar
PubMed:11090133
S - meiosis
perinucleolar
earliest replication origins of primary cells are often perinucleolar
PubMed:11090133
G1
repair foci
intranuclear foci esp early G1
PubMed:10984438
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
74.2
6.54
70
665
PubMed:10579712
Entrez Protein:NP_001002011
Uniprot:P48678
74.1
6.57
70
664
PubMed:10739764
PubMed:10587585
PubMed:10080180
PubMed:11257219
PubMed:10814726
PubMed:10655060
PubMed:11112685
PubMed:15317753
OMIM:604929
OMIM:181350
OMIM:159001
OMIM:151660
OMIM:115200
Entrez Protein:NP_733821
Uniprot:P02545
65.4
6.37
574
Entrez Protein:BAA08570
Uniprot:P11516
65.1
6.4
572
Entrez Protein:VEHULC
657
Entrez Protein:P13648
Uniprot:P13648
665
Entrez Protein:P48679
Uniprot:P48679
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0006997
nuclear organization and biogenesis
PubMed:11503164
PubMed:10579712
PubMed:11792811
PubMed:15184648
PubMed:15367494
PubMed:15317753
PubMed:12714972
PubMed:12702809
PubMed:12748643
PubMed:16126733
PubMed Central:14755333
pubmed:1860684
GO:0046716
muscle cell homeostasis
pubmed:21364987
Molecular Function
X
GO ID
Term
Links
Other Function
X
Function
Links
adipocyte differentiation
PubMed:16415042
Expression
X
Experiment
Detail
Links
Immunofluorescence
lamin A present in dermal fibroblasts and in suprabasal epithelial cells of skin
PubMed:11207047
Immunofluorescence
lamin A absent from all basal epithelial cells of skin
PubMed:11207047
Immunofluorescence
Lamin C expressed in dermal fibroblasts, suprabasal epithelial cells and a majority of basal epithelial cells.
PubMed:11207047
Immunofluorescence
Lamin C absent from quiescent basal epithelial cells of skin
PubMed:11207047
present in ESCs
pubmed:23324457
Related Genes
X
Name
Species
Links
lmn-1
Caenorhabditis elegans
PubMed:11071918
History
+