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Names
X
Name
Species
Main
lamin A/C
Gallus gallus, Homo sapiens, Mus musculus, Rattus norvegicus
True
Keywords
X
farnesylation, intermediary filament, replication origin, nuclear periphery
Location
X
Location
Species
3
Mus musculus
1q21.2-q21.3
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nuclear periphery
nuclear lamina
PubMed:15596010
G1
replication origins
earliest replication origins of primary cells
PubMed:11090133
PubMed:7738105
S - interphase
replication origins
earliest replication origins of primary cells
PubMed:11090133
G1
perinucleolar
earliest replication origins of primary cells are often perinucleolar
PubMed:11090133
S - meiosis
perinucleolar
earliest replication origins of primary cells are often perinucleolar
PubMed:11090133
G1
repair foci
intranuclear foci esp early G1
PubMed:10984438
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
74.2
6.54
70
665
PubMed:10579712
Entrez Protein:NP_001002011
Uniprot:P48678
74.1
6.57
70
664
PubMed:10739764
PubMed:10587585
PubMed:10080180
PubMed:11257219
PubMed:10814726
PubMed:10655060
PubMed:11112685
PubMed:15317753
OMIM:604929
OMIM:181350
OMIM:159001
OMIM:151660
OMIM:115200
Entrez Protein:NP_733821
Uniprot:P02545
65.4
6.37
574
Entrez Protein:BAA08570
Uniprot:P11516
65.1
6.4
572
Entrez Protein:VEHULC
657
Entrez Protein:P13648
Uniprot:P13648
665
Entrez Protein:P48679
Uniprot:P48679
Annotation
X
Start
End
Domain
Description
30
386
filament
219
222
NLS
408
545
IF_tail
417
420
NLS
662
665
farnesylation CaaX motif
219
222
NLS
417
420
NLS
661
664
farnesylation CaaX motif
219
222
NLS
417
420
NLS
219
222
NLS
417
420
NLS
Biological Process
X
GO ID
Term
Links
GO:0006997
nuclear organization and biogenesis
PubMed:11503164
PubMed:10579712
PubMed:11792811
PubMed:15184648
PubMed:15367494
PubMed:15317753
PubMed:12714972
PubMed:12702809
PubMed:12748643
PubMed:16126733
PubMed Central:14755333
pubmed:1860684
GO:0046716
muscle cell homeostasis
pubmed:21364987
Molecular Function
X
GO ID
Term
Links
Other Function
X
Function
Links
adipocyte differentiation
PubMed:16415042
Expression
+
Related Genes
X
Name
Species
Links
lmn-1
Caenorhabditis elegans
PubMed:11071918
History
+