APB, ATM, BRCA1 nuclear dots, cancer, chromosome breakage, chromosome instability, dna damage response, heterodimer, Ig hypermutation, Irradiation induced foci, telomere, nuclear foci, exonuclease, PML bodies, radiation sensitivity, molecular clamp, alt, alternative end-joining, ciliopathy, genetic disease, end resection
S - meiosis
PML/ND10 bodies
co-localisation with TRF1 in late S/G2
Interphase
IR-induced foci
to H2A-X foci after DNA damage together with brca1, rad50, nbs1
Interphase
telomere
role in t-loops?
G2
PML/ND10 bodies
co-localisation with TRF1 in late S/G2
S - interphase
replication foci
Interphase
ALT-associated PML body
in ALT cells
GO:0006261
DNA-dependent DNA replication
GO:0006302
double-strand break repair
GO:0006974
response to DNA damage stimulus
GO:0007003
telomere binding
GO:0016446
somatic hypermutation of antibody genes
GO:0000723
telomere maintenance
GO:0097681
double-strand break repair via alternative nonhomologous end joining
GO:0004518
nuclease activity
GOIDHERE
3.-5. exonuclease activity
AT-like disorder. radiosensitivity and an increased level of spontaneously occurring chromosome aberrations in peripheral blood lymphocytes
MRE11
Saccharomyces cerevisiae
mre
Caenorhabditis elegans
2001-04-17 16:23:11
2006-02-15 09:14:22