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Names
X
Name
Species
Main
RECQL2
Homo sapiens
False
WRN
Homo sapiens
True
Keywords
+
Location
X
Location
Species
8A4
Mus musculus
8p12-p11.2
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nucleolus
only in proliferating human cells. Nucleoplasmic in serum starved cell, after ActD, + in the mouse.
PubMed:11420665
PubMed:11971179
PubMed:15635413
PubMed Central:98284027
PubMed Central:11027336
S - meiosis
repair foci
with RP-A in hydroxyurea arrested cells
PubMed:11256630
Interphase
repair foci
with RPA and rad51 after DNA damage. Partial co-localisation with PML bodies
PubMed:11380620
PubMed:12384494
PubMed:17118963
PubMed:16141234
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
162.5
5.96
1432
Entrez Protein:Q14191
PubMed:0010647186
PubMed:11257107
OMIM:277700
Uniprot:Q14191
157.3
6.1
1401
Entrez Protein:NP_035851
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0006281
DNA repair
PubMed:11257107
GO:0006261
DNA-dependent DNA replication
pubmed:18209099
GO:0006312
mitotic recombination
PubMed:11316787
GO:0000723
telomere maintenance
PubMed:15591207
GO:0006360
transcription from Pol I promoter
PubMed:11971179
GO:1902153
regulation of response to DNA damage checkpoint signaling
pubmed:2215942
GO:0070828
heterochromatin organization
pubmed:25931448
Molecular Function
X
GO ID
Term
Links
GO:0008408
3.-5. exonuclease activity
PubMed:11257107
GO:0003684
damaged DNA binding
PubMed:14534320
GO:0003678
DNA helicase activity
PubMed:11257107
GO:0044806
G-quadruplex DNA unwinding
pubmed:30279242
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
RecQ
Escherichia coli
Sgs1
Saccharomyces cerevisiae
PubMed:11179234
PubMed:11290710
ffa-1
Xenopus laevis
PubMed:11238454
Rqh1
Schizosaccharomyces pombe
History
X
Created On
Last Changed
2001-04-23 13:06:09
2006-07-13 16:14:51