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Names
X
Name
Species
Main
TCOF-1
Homo sapiens, Mus musculus
True
treacle
Homo sapiens
False
Keywords
X
genetic disease, LisH, nucleolus, rRNA transcription, dna damage response, kinetochore, centrosome, spindle orientation, Treacher Collins syndrome
Location
+
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nucleolar
PubMed:11790298
PubMed:9811939
PubMed:9736782
pubmed:25064736
Interphase
actinomycin D
nucleolar cap
PubMed:15249688
Interphase
centrosome
pubmed:22479190
metaphase - mitosis
kinetochore
pubmed:22479190
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
144.3
9.06
1411
Entrez Protein:Q13428
PubMed:9736782
OMIM:154500
Uniprot:Q13428
1320
Entrez Protein:NP_035682
PubMed:9158147
Annotation
X
Start
End
Domain
Description
5
8
NLS
6
38
lisH
61
78
NLS BP
907
1003
NLS
1049
1052
NLS
1194
1203
NLS
1270
1289
NLS BP
1359
1405
NLS BP
Biological Process
X
GO ID
Term
Links
GO:0001510
RNA methylation
PubMed:15930015
GO:0006364
rRNA processing
PubMed:15930015
GO:0006356
regulation of transcription from Pol I promoter
PubMed:15249688
pubmed:19527688
GO:0022008
neurogenesis
pubmed:22479190
GO:0007067
mitosis
pubmed:22479190
GO:0051294
establishment of spindle orientation
pubmed:22479190
GOIDHERE
DNA damage response, detection of DNA damage
pubmed:25064736
Molecular Function
X
GO ID
Term
Links
GO:0001042
RNA polymerase I core binding
pubmed:19527688
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
History
+