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Names
X
Name
Species
Main
HDM2
Homo sapiens
False
MDM2
Homo sapiens, Mus musculus
True
Keywords
+
Location
X
Location
Species
12q14.3-q15
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nucleolar
PubMed:11306450
PubMed:15195100
PubMed:16129783
Interphase
nuclear-cytoplasmic shuttling
shuttling prevented by p14ARF
PubMed:11306450
Interphase
PML/ND10 bodies
after overexpression of PML
PubMed:12915590
pubmed:18264029
Interphase
IR-induced foci
PubMed:15734743
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
55.2
4.2
491
Entrez Protein:Q00987
PubMed:11313871
OMIM:164785
Uniprot:Q00987
489
Entrez Protein:P23804
Uniprot:P23804
Annotation
X
Start
End
Domain
Description
181
185
NLS
438
478
RING finger
Biological Process
X
GO ID
Term
Links
GO:0006302
double-strand break repair
PubMed:15734743
GO:0016574
histone ubiquitination
PubMed:15546622
GO:0007049
cell cycle
PubMed:14707284
PubMed:14704432
GO:0019827
stem cell maintenance
pubmed:26748827
GO:0006340
negative regulation of transcription of homeotic gene (Polycomb group)
pubmed:26748827
Molecular Function
X
GO ID
Term
Links
GO:0004842
ubiquitin-protein ligase activity
PubMed:20187618
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
MDM2
Xenopus laevis
Uniprot:P56273
History
X
Created On
Last Changed
2001-05-02 09:48:35
2005-05-04 12:57:22