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Names
X
Name
Species
Main
p53
Homo sapiens
True
TP53
False
LFS1
false
Keywords
+
Location
X
Location
Species
17p13.1
Mus musculus
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nuclear-cytoplasmic shuttling
shuttles. Accumulates in nucleus after stress. Monoubiquitination leads to nuclear export.
PubMed:11329373
Interphase
nucleolar
In cells treated with MG132 and in nucleolar cavities
PubMed:11329373
pubmed: 20332106
pubmed:25723258
Interphase
Cajal bodies
PubMed:11704667
Interphase
PML/ND10 bodies
interaction with HIPK2
PubMed:11740489
Interphase
IR-induced foci
with gamma H2A.X and ATM
PubMed:16322227
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
43.7
6.48
53
393
OMIM:151623
OMIM:191170
Entrez Protein:NP_000537
Uniprot:P04637
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0006915
apoptosis
PubMed:9305847
GO:0006338
chromatin remodeling
PubMed:12574133
GO:0000122
negative regulation of transcription from Pol II promoter
PubMed:15531928
GO:0006289
nucleotide-excision repair
PubMed:12574133
GO:0006974
response to DNA damage stimulus
GO:0006357
regulation of transcription from Pol II promoter
PubMed:8414502
GO:0031937
positive regulation of chromatin silencing
pubmed: 33060137
Molecular Function
X
GO ID
Term
Links
GO:0003682
chromatin binding
PubMed:11511360
GO:0003677
DNA binding
PubMed: 8276238
PubMed:11511360
PubMed:8414502
GO:0000981
sequence-specific DNA binding RNA polymerase II transcription factor activity
pubmed:25391375
Other Function
X
Function
Links
Expression
+
Related Genes
X
Name
Species
Links
History
+