Names
X
Name
Species
Main
KAP-1 
Homo sapiens, Mus musculus 
True 
KRIP1 
Mus musculus 
False 
TF1B 
Mus musculus 
False 
TIF1-beta 
Homo sapiens, Mus musculus 
False 
TRIM28 
 
False 
KAP1 
 
false 
Keywords
X
bromodomain, ds break repair, histone methylation, Irradiation induced foci, RBCC, repression complex, transcription repression, zinc finger B_box, PxVxL, PML bodies, proviral silencing, imprinting, DNA end-resection
Location
X
Location
Species
19q13.4 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
heterochromatin 
co-localisation with HP1-alpha. In differentiated cells. Requires HP1 
PubMed:10562550
PubMed:11278721
PubMed:10330177
meiosis 
chromosomal 
 
PubMed:11973266
Interphase 
diffuse nuclear 
in undifferentiated cells and in TSA treated cells 
PubMed:11278721
PubMed:12154074
Interphase 
IR-induced foci 
 
PubMed:17178852
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
88.5 
5.52 
100 
 
835 
Entrez Protein:NP_005753
PubMed:11226167
PubMed:8769649
OMIM:601742
Uniprot:Q13263
PubMed Central:11171966
88.8 
5.52 
 
 
834 
Entrez Protein:Q62318
PubMed:11278721
PubMed:10851139
Uniprot:Q62318
Annotation
X
Start
End
Domain
Description
65 
120 
RING finger 
 
148 
195 
B-Box Zn finger 
 
204 
245 
B-Box Zn finger 
 
252 
378 
BBC 
 
627 
670 
PHD finger 
 
697 
801 
Bromo 
 
66 
121 
RING finger 
 
149 
196 
B-Box Zn finger 
 
205 
246 
B-Box Zn finger 
 
253 
379 
BBC 
 
627 
670 
PHD finger 
 
697 
801 
Bromo 
 
Biological Process
X
GO ID
Term
Links
GO:0006342 
chromatin silencing 
PubMed:10562550
PubMed:10938122
PubMed:11230151
PubMed:12869583
PubMed:17298944
PubMed Central:11171966
pubmed:18713861
GO:0006302 
double-strand break repair 
PubMed:16862143
pubmed:24842905
GO:0000122 
negative regulation of transcription from Pol II promoter 
pubmed:20075919
pubmed:22544392
GO:0001672 
regulation of chromatin assembly or disassembly 
PubMed:16862143
GO:0045091 
regulation of retroviral genome replication 
pubmed:18713861
GO:0030578 
PML body organization 
pubmed:21228624
GO:0071514 
genetic imprinting 
pubmed:22442485
Molecular Function
X
GO ID
Term
Links
GO:0003682 
chromatin binding 
PubMed:10562550
PubMed:15882967
Other Function
X
Function
Links
embryonic lethal 
pubmed:22442485
Expression
X
Experiment
Detail
Links
Northern 
ubiquitous 
PubMed:9016654
Related Genes
X
Name
Species
Links
bonus 
Drosophila melanogaster 
PubMed:11336699
History
X
Created On
Last Changed
2001-05-08 14:29:09 
2007-07-27 11:31:00