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Names
X
Name
Species
Main
DDX21
False
DEAD BOX protein 21
Homo sapiens
False
GURDB
Homo sapiens
False
RH-II/Gualpha
False
RHII
Homo sapiens, Mus musculus
False
RNA helicase GU
Homo sapiens, Mus musculus
False
RNA helicase II
Homo sapiens, Mus musculus
True
Keywords
X
autoantigen, chromosome scaffold, helicase, rRNA transcription, mitotic chromosomes, nuclear mRNA splicing via spliceosome, RNA binding, RH_II_Gualpha, guanine quadruplexes, R loops, granular component, ribosome biogenesis, transcription elongation, innate immunity
Location
X
Location
Species
10
Mus musculus
10q21
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nucleolus
becomes nucleoplasmic with ActD or anisomycin, UV or JNK signalling
pubmed:25470060
PubMed:11790298
PubMed:12429849
PubMed:11823437
PubMed:15635413
PubMed:9631199
pubmed:23848194
Mitosis
chromosomal
PubMed:15609038
Interphase
cytoplasm
after viral infection
pubmed:27033607
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
79.7
9.42
715
Entrez Protein: Q9NR30
93.6
9.19
851
Entrez Protein:Q9JIK5
Annotation
X
Start
End
Domain
Description
4
10
NLS
28
46
NLS BP
60
68
NLS
137
344
DEAD box
380
464
Helicase
26
32
NLS
60
76
NLS BP
125
133
NLS
162
170
NLS
199
207
NLS
277
484
DEAD box
524
604
Helicase
Biological Process
X
GO ID
Term
Links
GO:0000398
nuclear mRNA splicing, via spliceosome
PubMed:12176931
GO:0006364
rRNA processing
PubMed:14559904
GO:0006357
regulation of transcription from Pol II promoter
pubmed:25470060
pubmed:11823437
GO:0006356
regulation of transcription from RNA polymerase I promoter
pubmed:25470060
pubmed:29364875
GO:0006356
regulation of transcription from RNA polymerase I promoter
pubmed:25470060
GO:0006356
regulation of transcription from RNA polymerase I promoter
pubmed:25470060
GO:0042273
ribosomal large subunit biogenesis
pubmed:25477391
GOIDHERE
genome stability
pubmed:28790157
pubmed:28472472
pubmed:28790157
GO:2001208
negative regulation of transcription elongation from RNA polymerase I promoter
pubmed:25470060
GO:0045087
innate immune response
pubmed:27033607
Molecular Function
X
GO ID
Term
Links
GO:0003724
RNA helicase activity
PubMed:11029582
GO:0003723
RNA binding
pubmed:25470060
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2001-06-26 18:40:47
2005-01-19 16:42:13