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Names
X
Name
Species
Main
DAP70
False
DDX5
Homo sapiens, Mus musculus
False
DDX59
False
DEAD-BOX PROTEIN 5
Homo sapiens, Mus musculus
False
DEAD-BOX PROTEIN P68
Homo sapiens, Mus musculus
False
HLR1
False
P68 helicase
Homo sapiens, Mus musculus
True
RNA HELICASE, 68-KD
False
Keywords
X
ActD movement, splicing speckles, nucleolus, miRNA processing, mitotic chromosomes, nuclear mRNA splicing via spliceosome, prespliceosome, insulation, genetic disease, alternative splicing
Location
X
Location
Species
17q21-q25
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nuclear diffuse
nuclear matrix
PubMed:11279182
telophase
nucleolus
associates with PNBs in late telophase, not in nucleolus at interphase.
PubMed:10837141
Interphase
splicing speckles
identified during in vitro spliceosome assembly
PubMed:15657085
PubMed:9731529
actinomycin D
perinucleolar
after ActD
Interphase
nucleolus
PubMed:12429849
PubMed:11790298
PubMed:15635413
Mitosis
heterochromatin
PubMed:15657085
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
69.1
9.06
68
614
Entrez Protein:NP_004387
OMIM:180630
Uniprot:P17844
PubMed:23972372
69.3
9.06
Entrez Protein:Q61656
Annotation
X
Start
End
Domain
Description
113
316
DEAD box
355
436
Helicase
113
316
DEAD box
355
436
Helicase
Biological Process
X
GO ID
Term
Links
GO:0030918
microRNA processing
PubMed:15531877
GO:0007517
muscle development
PubMed:17011493
GO:0000398
nuclear mRNA splicing, via spliceosome
PubMed:12176931
PubMed:11991638
PubMed:12477934
PubMed:9731529
GOIDHERE
establishment and/or maintenance of chromatin architecture
pubmed:20966046
GOIDHERE
alternative mRNA splicing, via spliceosome
pubmed:30042133
Molecular Function
X
GO ID
Term
Links
GO:0003724
RNA helicase activity
PubMed:11353078
GO:0003714
transcription corepressor activity
PubMed:15298701
Other Function
X
Function
Links
associates with HDAC1
PubMed:15298701
nucleolar assembly?
Expression
X
Experiment
Detail
Links
palate and limb buds
pubmed: 23972372
Related Genes
X
Name
Species
Links
Dbp2
Schizosaccharomyces pombe
Dbp2
Saccharomyces cerevisiae
History
+