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Names
X
Name
Species
Main
DNA (cytosine-5-)-methyltransferase 1
Homo sapiens
False
DNA methyltransferase 1
Homo sapiens, Mus musculus
False
DNMT1
Homo sapiens, Mus musculus
True
maintenance methylase
Homo sapiens
False
CXXC9
false
Keywords
X
ds break repair, repair foci, DNA repair, dna methylase, histone deacetylase complex, histone methylation, replication origin, repression complex, zinc finger CXXC, dna damage response, genetic disease, hearing loss, cognitive decline, HSN1E, ADCADN
Location
X
Location
Species
19p13.2
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
replication origins
PubMed:10888872
S - interphase
heterochromatin
in late S, together with HDAC2 and DMAP
PubMed:10888872
Interphase
IR-induced foci
pubmed:20940144
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
183.2
7.99
1616
Entrez Protein:NP_001370
Uniprot:P26358
PubMed: 21532572
PubMed:22328086
PubMed:23365052
PubMed:25678562
183.3
8.37
1620
Entrez Protein:CAA32910
Uniprot:P13864
Annotation
X
Start
End
Domain
Description
16
106
dmap binding
21
27
NLS
138
144
NLS
175
181
NLS
203
206
NLS
243
259
NLS BP
284
300
NLS BP
323
339
NLS BP
645
691
CXXC Zn finger
649
652
NLS
722
725
NLS
755
880
bah
931
1100
bah
955
961
NLS
1139
1594
DNA methylase
21
27
NLS
135
141
NLS
172
178
NLS
198
201
NLS
289
296
NLS
319
322
NLS
326
343
NLS BP
651
654
NLS
724
727
NLS
757
833
bah
958
964
NLS
969
1103
bah
1141
1596
DNA methylase
Biological Process
X
GO ID
Term
Links
GO:0006915
apoptosis
PubMed:11137995
GO:0006338
chromatin remodeling
PubMed:15220328
GO:0006306
DNA methylation
PubMed:11399088
GO:0006349
imprinting
PubMed:11290321
GO:0006918
induction of apoptosis by p53
PubMed:11137995
GO:0006346
methylation-dependent chromatin silencing
PubMed:10888872
PubMed:11137995
PubMed:10888886
GO:0006281
DNA damage response, detection of DNA damage
pubmed:20940144
Molecular Function
X
GO ID
Term
Links
GO:0003886
DNA (cytosine-5-)-methyltransferase activity
PubMed:11399088
GO:0045322
unmethylated CpG binding
pubmed:21163962
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
xDnmt1
Xenopus laevis
PubMed:11296229
History
X
Created On
Last Changed
2001-07-05 15:39:18
2004-12-04 20:37:52