growth, dna methylase, gene trap, histone deacetylase complex, histone methylation, PWWP domain, mitotic chromosomes, repression complex, transcription repression, methyl-lysine binding, ADD domain, transcription elongation, H3K36me3 binding, genetic disease, acute leukemia, cancer, differentiation, mutated in cancer, AML, Tatton-Brown-Rahman syndrome, overgrowth
Interphase
heterochromatin
Interphase
nuclear diffuse
gene -trap is nuclear diffuse. Dnmt3a2 isoform is also diffuse over chromatin
Mitosis
chromosomal
depends on PWWP domain
1
209
gene trap insertion
GO:0006338
chromatin remodeling
GO:0006306
DNA methylation
GO:0006346
methylation-dependent chromatin silencing
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
GO:0048863
stem cell differentiation
GO:0003886
DNA (cytosine-5-)-methyltransferase activity
GO:0035064
methylated histone residue binding
2001-07-05 16:20:38
2004-12-04 20:37:52