or browse by
compartment
or
motif
About
Links
Statistics
Web Services
FAQs
Names
X
Name
Species
Main
DNA (cytosine-5-)-methyltransferase 3b
Homo sapiens, Mus musculus
False
Dnmt3b
Homo sapiens, Mus musculus
True
Keywords
X
PWWP domain, chromosome instability, dna methylase, genetic disease, E2F, DNA methylation, mental retardation
Location
X
Location
Species
20q11.2
Homo sapiens
2
Mus musculus
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
pericentric heterochromatin
in mouse fibroblasts
PubMed:11427539
PubMed:12867029
PubMed:15456878
Interphase
nuclear diffuse
in ES cells
PubMed:11427539
Mitosis
chromosomal
depends on PWWP domain
PubMed:14998998
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
95.8
8.74
853
Entrez Protein:NP_008823
PubMed:10647011
OMIM:602900
OMIM:242860
Uniprot:Q9UBC3
PubMed Central:10588719
PubMed:27153398
87.6
7.91
859
Entrez Protein:O88509
PubMed:10555141
Uniprot:O88509
Annotation
X
Start
End
Domain
Description
44
50
NLS
223
281
PWWP
368
384
NLS BP
394
402
NLS
477
530
PHD finger
537
540
NLS
568
574
NLS
575
848
DNA methylase
54
60
NLS
157
165
NLS
232
290
PWWP
362
368
NLS
380
388
NLS
482
535
PHD finger
522
525
NLS
554
560
NLS
581
854
DNA methylase
Biological Process
X
GO ID
Term
Links
GO:0006306
DNA methylation
PubMed:10555141
PubMed:12110732
GO:0006325
establishment and/or maintenance of chromatin architecture
PubMed:10588719
PubMed:15856360
GO:0006346
methylation-dependent chromatin silencing
PubMed:11063717
PubMed:11741835
pubmed:20439742
GO:0030261
chromosome condensation
PubMed:15148359
Molecular Function
X
GO ID
Term
Links
GO:0003886
DNA (cytosine-5-)-methyltransferase activity
PubMed:10555141
GO:0003677
DNA binding
PubMed:11836534
Other Function
X
Function
Links
immunodeficiency in ICF
OMIM:242860
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2001-07-05 16:48:45
2004-12-04 20:37:52