or browse by
compartment
or
motif
About
Links
Statistics
Web Services
FAQs
Names
X
Name
Species
Main
HIF-1 alpha
Homo sapiens, Mus musculus
True
MOP1
False
bHLHe78
false
PASD8
false
HIF-1A
false
HIF1 alpha
false
HIF1A
false
Keywords
+
Location
X
Location
Species
14q23.2
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nuclear diffuse
Heterodimer with HIF1-beta.
Interphase
nucleolus
sequestered to nucleolus by p14ARF
PubMed:11382768
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
95.5
5.17
850
Entrez Protein:NP_001230013
PubMed:11313887
Uniprot:Q16665
91.9
5.17
822
Entrez Protein:Q61221
Uniprot:Q61221
Annotation
X
Start
End
Domain
Description
17
33
NLS BP
23
78
HLH
87
153
PAS
230
296
PAS
302
345
PAC
718
721
NLS
17
33
NLS BP
23
78
HLH
87
153
PAS
154
160
NLS
230
296
PAS
302
345
PAC
714
717
NLS
Biological Process
X
GO ID
Term
Links
GO:0006357
regulation of transcription from Pol II promoter
PubMed Central:10758161
GO:0032364
oxygen homeostasis
pubmed:7539918
GO:0060612
adipose tissue development
pubmed:11879638
Molecular Function
X
GO ID
Term
Links
GO:0003677
DNA binding
PubMed Central:10758161
GO:0003704
specific RNA polymerase II transcription factor activity
PubMed Central:10758161
Other Function
X
Function
Links
angiogenesis, erythropoiesis and glycolysis
PubMed Central:10758161
induction of oxygen regulated genes. Heterodimer with HIF1-beta.
PubMed Central:10758161
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
HIF-1 alpha
Caenorhabditis elegans
PubMed:11427734
History
X
Created On
Last Changed
2001-07-12 11:03:19
2004-12-02 15:29:43