predominantly endothelial cells, transcription factor, hypoxia, HLH, pas domain, genetic disease
Interphase
nuclear diffuse
GO:0006357
regulation of transcription from Pol II promoter
GO:0032364
oxygen homeostasis
GO:0003704
specific RNA polymerase II transcription factor activity
activates transcription of the endothelial tyrosine kinase gene Tie-2
remodeling of the primary vascular network into a mature hierarchy pattern