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Names
X
Name
Species
Main
H3-K9-HMTase 1
Homo sapiens, Mus musculus
False
Su(var)3-9 homolog 1
False
SUV39H1
Homo sapiens, Mus musculus
True
KMT1A
false
Keywords
X
H3K9 methylation, aneuploidy, centromere protein, chromodomain, chromosome scaffold, chromosome segregation, chromosome synapsis, histone methylase, set domain, meiotic chromosomes, meiotic prophase, mitotic chromosomes, PEV, protein methyltransferase, telomere
Location
X
Location
Species
Xp11.23.
Homo sapiens
X
Mus musculus
Subcellular Localisation
X
Stage
Description
Details
Links
prophase - mitosis
centromere
PubMed:10671371
PubMed:10202156
metaphase - mitosis
centromere
coincides with phosphorylation
PubMed:10671371
PubMed:15609038
Interphase
heterochromatin
PubMed:10779362
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
47.8
8.35
412
Entrez Protein:NP_035644
Uniprot:O54864
47.9
8.38
412
Entrez Protein:XP_010187
Uniprot:O43463
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0007002
centromere binding
PubMed:10949293
GO:0006342
chromatin silencing
PubMed:12101246
GO:0006306
DNA methylation
PubMed:12867029
GO:0006325
establishment and/or maintenance of chromatin architecture
PubMed:11242054
PubMed:11242053
PubMed:10949293
GO:0016571
histone methylation
PubMed:10949293
GO:0007004
telomerase-dependent telomere maintenance
PubMed:14702045
GO:0006344
maintenance of chromatin silencing
PubMed:10990462
PubMed:12101246
GO:0007128
meiotic prophase I
PubMed:11701123
GO:0000070
mitotic sister chromatid segregation
PubMed:10949293
PubMed:11701123
Molecular Function
X
GO ID
Term
Links
GO:0046974
histone lysine N-methyltransferase activity (H3-K9 specific)
PubMed:10949293
GO:0016278
lysine N-methyltransferase activity
pubmed: 22078878
Other Function
X
Function
Links
surviving double nulls are growth retarded. Develop B cell lymphomas. Males are infertile
PubMed:11701123
Expression
+
Related Genes
X
Name
Species
Links
Su(var)3-9
Drosophila melanogaster
PubMed:10202156
Clr4
Schizosaccharomyces pombe
PubMed:10949293
History
+