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Names
X
Name
Species
Main
H3-K9-HMTase 1
Homo sapiens, Mus musculus
False
Su(var)3-9 homolog 1
False
SUV39H1
Homo sapiens, Mus musculus
True
KMT1A
false
Keywords
+
Location
X
Location
Species
Xp11.23.
Homo sapiens
X
Mus musculus
Subcellular Localisation
X
Stage
Description
Details
Links
prophase - mitosis
centromere
PubMed:10671371
PubMed:10202156
metaphase - mitosis
centromere
coincides with phosphorylation
PubMed:10671371
PubMed:15609038
Interphase
heterochromatin
PubMed:10779362
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
47.8
8.35
412
Entrez Protein:NP_035644
Uniprot:O54864
47.9
8.38
412
Entrez Protein:XP_010187
Uniprot:O43463
Annotation
X
Start
End
Domain
Description
42
94
Chromo
99
103
NLS
132
227
preSET
243
372
SET
389
398
NLS
396
412
post SET
42
94
Chromo
132
227
preSET
243
372
SET
389
398
NLS
396
412
post SET
Biological Process
X
GO ID
Term
Links
GO:0007002
centromere binding
PubMed:10949293
GO:0006342
chromatin silencing
PubMed:12101246
GO:0006306
DNA methylation
PubMed:12867029
GO:0006325
establishment and/or maintenance of chromatin architecture
PubMed:11242054
PubMed:11242053
PubMed:10949293
GO:0016571
histone methylation
PubMed:10949293
GO:0007004
telomerase-dependent telomere maintenance
PubMed:14702045
GO:0006344
maintenance of chromatin silencing
PubMed:10990462
PubMed:12101246
GO:0007128
meiotic prophase I
PubMed:11701123
GO:0000070
mitotic sister chromatid segregation
PubMed:10949293
PubMed:11701123
Molecular Function
X
GO ID
Term
Links
GO:0046974
histone lysine N-methyltransferase activity (H3-K9 specific)
PubMed:10949293
GO:0016278
lysine N-methyltransferase activity
pubmed: 22078878
Other Function
X
Function
Links
surviving double nulls are growth retarded. Develop B cell lymphomas. Males are infertile
PubMed:11701123
Expression
+
Related Genes
X
Name
Species
Links
Su(var)3-9
Drosophila melanogaster
PubMed:10202156
Clr4
Schizosaccharomyces pombe
PubMed:10949293
History
X
Created On
Last Changed
2001-07-12 17:03:55
2005-01-21 13:59:31