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Names
X
Name
Species
Main
lamin B receptor
False
LBR
Gallus gallus, Homo sapiens
True
LMN2R
False
p58
False
Keywords
X
genetic disease, heterochromatin binding, PxVxL, integral membrane protein, mitotic chromosomes, nuclear periphery, SR_RS domain, inm, histone binding, cholesterol biosynthesis, ER, methylated H4K20 binding, tudor, sterol reductase
Location
X
Location
Species
1q42.1
Homo sapiens
1
Mus musculus
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
inner nuclear membrane
inner nuclear membrane
PubMed:9003786
anaphase - mitosis
chromosome surface
recruited before emerin and in more peripheral location
PubMed:10671368
Interphase
endoplasmic reticulum
pubmed:21327084
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
70.7
9.41
615
Entrez Protein:NP_919424
PubMed:12118250
PubMed:12490533
PubMed:12618959
OMIM:169400
Uniprot:Q14739
PubMed:9878250
637
Entrez Protein:P23913
Uniprot:P23913
626
Entrez Protein:NP_598576
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0006325
establishment and/or maintenance of chromatin architecture
PubMed:15882967
PubMed:9169472
GO:0006998
nuclear membrane organization and biogenesis
PubMed:12118250
PubMed:14617022
PubMed:9003786
GO:0016126
cholesterol biosynthetic process
pubmed:22140257
Molecular Function
X
GO ID
Term
Links
GO:0042393
histone binding
pubmed:22052904
GO:0050613
delta14-sterol reductase activity
pubmed:22140257
GO:0035064
methylated histone binding
pubmed:23100253
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
History
+