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Names
X
Name
Species
Main
DNA-dependent protein kinase catalytic subunit
False
DNA-PK
False
DNA-PKCS
Homo sapiens, Mus musculus
True
DNPK1
False
PRKDC
False
Keywords
X
ATM, chromosome instability, DNA damage, DNA repair, ds break repair, fat domain, linker histone phosphorylation, nhej, PI3kinase, telomere
Location
X
Location
Species
8q11
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
S - interphase
nuclear diffuse
cytoplasmic in G1, moves to nucleus in G1/S
PubMed:10614713
Interphase
nucleolus
PubMed:11790298
PubMed:12429849
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
469.1
6.78
4128
Entrez Protein:P78527
PubMed:15698568
PubMed:95401275
OMIM:600899
Uniprot:P78527
4128
Entrez Protein:P97313
Uniprot:P97313
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0006302
double-strand break repair
PubMed:10854421
GO:0006303
double-strand break repair via nonhomologous end-joining
PubMed:10854421
PubMed:15574326
GO:0016572
histone phosphorylation
PubMed:15671175
GO:0007004
telomerase-dependent telomere maintenance
PubMed:11340158
PubMed:11742099
GO:0006975
DNA damage induced protein phosphorylation
PubMed:15059890
PubMed:15389585
Molecular Function
X
GO ID
Term
Links
GO:0004677
DNA-dependent protein kinase activity
PubMed:10854421
Other Function
X
Function
Links
SCID mutation
PubMed:9398856
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
TOR1
Saccharomyces cerevisiae
PubMed:11790298
History
+