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Names
X
Name
Species
Main
ATR
Homo sapiens
True
FRP1
Homo sapiens
False
FCTCS
false
MEC1
false
SCKL
false
SCKL1
false
Keywords
+
Location
X
Location
Species
3q22-q24
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
BRCA1 nuclear dots
co-localisation with brca1 after damage
PubMed:12814551
Interphase
replication foci
co-localisation with stalled replication forks
Interphase
nucleolus
PubMed:11790298
prophase - meiosis
axial elements of synaptonemal complex
unsynapsed elements
PubMed:9443891
Interphase
PML/ND10 bodies
PubMed:12814551
pachytene
XY body
PubMed:15998665
PubMed:15589157
Interphase
cilia
in photoreceptors
pubmed:23297361
S phase
nuclear periphery
pubmed:25083873
prophase - mitosis
nuclear periphery
pubmed:25083873
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
301.5
7.23
2644
OMIM:601215
Entrez Protein:NP_001175
Uniprot:Q13535
PubMed:23111928
PubMed:12640452
Annotation
X
Start
End
Domain
Description
429
446
NLS BP
430
447
NLS BP
525
528
NLS
805
839
heat
1119
1125
UME
1329
1365
heat
1640
2185
fat
1699
1732
TPR
2308
2311
NLS
2323
2633
PI3Kc
2612
2644
fatc
Biological Process
X
GO ID
Term
Links
GO:0000077
DNA damage checkpoint
PubMed:10859164
GO:0006281
DNA repair
PubMed:11114888
PubMed:10859164
PubMed:11418864
PubMed:11278964
PubMed:12526805
PubMed:15314022
GO:0006975
DNA damage induced protein phosphorylation
PubMed:11114888
PubMed:10859164
PubMed:11799063
GO:0016446
somatic hypermutation of antibody genes
PubMed:16390936
GO:0016447
somatic recombination of antibody genes
PubMed:16390936
GO:0007128
meiotic prophase I
pubmed:29976923
Molecular Function
X
GO ID
Term
Links
GO:0003684
damaged DNA binding
PubMed:12011431
GO:0004674
protein serine/threonine kinase activity
PubMed:10859164
Other Function
X
Function
Links
caspase-independent chromosome breaks are observed in ATR(-/-) cells
PubMed:10691732
embryonic lethal E8.5
PubMed:10801416
Expression
+
Related Genes
X
Name
Species
Links
Rad3
Schizosaccharomyces pombe
PubMed:97133293
Esr1
Saccharomyces cerevisiae
PubMed:97133293
Mec1
Saccharomyces cerevisiae
History
X
Created On
Last Changed
2001-07-16 16:28:05
2006-02-24 10:26:02