Names
X
Name
Species
Main
ATR 
Homo sapiens 
True 
FRP1 
Homo sapiens 
False 
FCTCS 
 
false 
MEC1 
 
false 
SCKL 
 
false 
SCKL1 
 
false 
Keywords
+
Location
X
Location
Species
3q22-q24 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
BRCA1 nuclear dots 
co-localisation with brca1 after damage 
PubMed:12814551
Interphase 
replication foci 
co-localisation with stalled replication forks 
Interphase 
nucleolus 
 
PubMed:11790298
prophase - meiosis 
axial elements of synaptonemal complex 
unsynapsed elements 
PubMed:9443891
Interphase 
PML/ND10 bodies 
 
PubMed:12814551
pachytene 
XY body 
 
PubMed:15998665
PubMed:15589157
Interphase 
cilia 
in photoreceptors 
pubmed:23297361
S phase 
nuclear periphery 
 
pubmed:25083873
prophase - mitosis 
nuclear periphery 
 
pubmed:25083873
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
301.5 
7.23 
 
 
2644 
OMIM:601215
Entrez Protein:NP_001175
Uniprot:Q13535
PubMed:23111928
PubMed:12640452
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0000077 
DNA damage checkpoint 
PubMed:10859164
GO:0006281 
DNA repair 
PubMed:11114888
PubMed:10859164
PubMed:11418864
PubMed:11278964
PubMed:12526805
PubMed:15314022
GO:0006975 
DNA damage induced protein phosphorylation 
PubMed:11114888
PubMed:10859164
PubMed:11799063
GO:0016446 
somatic hypermutation of antibody genes 
PubMed:16390936
GO:0016447 
somatic recombination of antibody genes 
PubMed:16390936
GO:0007128 
meiotic prophase I 
pubmed:29976923
Molecular Function
X
GO ID
Term
Links
GO:0003684 
damaged DNA binding 
PubMed:12011431
GO:0004674 
protein serine/threonine kinase activity 
PubMed:10859164
Other Function
X
Function
Links
caspase-independent chromosome breaks are observed in ATR(-/-) cells 
PubMed:10691732
embryonic lethal E8.5 
PubMed:10801416
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
Rad3 
Schizosaccharomyces pombe 
PubMed:97133293
Esr1 
Saccharomyces cerevisiae 
PubMed:97133293
Mec1 
Saccharomyces cerevisiae 
History
X
Created On
Last Changed
2001-07-16 16:28:05 
2006-02-24 10:26:02