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Names
X
Name
Species
Main
ATM
Homo sapiens, Mus musculus
True
TEL1
false
Keywords
X
ataxia, cancer, chromatin remodelling, chromosome breakage, DNA damage, ds break repair, fat domain, homologous recombination, nhej, Ig class switching, immunodeficiency, Irradiation induced foci, kinase, meiotic chromosomes, meiotic prophase, meiotic recombination, PI3kinase, radiation sensitivity, recombination, telomere, VDJ recombination, heat repeats
Location
X
Location
Species
9C
Mus musculus
11q22.3
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nuclear diffuse
but resists extraction after ds break
PubMed:11454856
PubMed:12556884
PubMed:9150358
PubMed:97294602
Interphase
cytoplasmic
in vesicles associated with beta-adaptin
PubMed:97294602
PubMed Central:98374320
Interphase
IR-induced foci
unextractable form co-localises with H2A.X after ds break induction
PubMed:11454856
PubMed:12556884
prophase - meiosis
synaptonemal complex
synapsed
PubMed:9443891
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
350.6
6.34
370
3056
Entrez Protein:NP_000042
OMIM:208900
Uniprot:Q13315
349.5
6.45
3066
Entrez Protein:Q62388
Annotation
X
Start
End
Domain
Description
383
389
NLS
1434
1437
NLS
1966
2566
fat
2655
2698
AraC HTH
2713
3106
PI3Kc
2746
2749
NLS
3024
3056
fatc
382
388
NLS
1441
1444
NLS
1972
2576
fat
2665
2708
AraC HTH
2723
3026
PI3Kc
2756
2759
NLS
3034
3066
fatc
5
166
tan
Biological Process
X
GO ID
Term
Links
GO:0006338
chromatin remodeling
PubMed:11877376
PubMed:11571274
GO:0000077
DNA damage checkpoint
PubMed:12447390
PubMed:15790808
GO:0006302
double-strand break repair
PubMed:10550055
GO:0001649
osteoblast differentiation
PubMed:16601153
GO:0007004
telomerase-dependent telomere maintenance
PubMed:11604086
GO:0006975
DNA damage induced protein phosphorylation
PubMed:10550055
PubMed:11181576
PubMed:11877376
PubMed:11571274
PubMed:15389585
PubMed:15059890
GO:0016447
somatic recombination of antibody genes
PubMed:11799059
PubMed:15520243
PubMed:16799570
GO:0000724
double-strand break repair via homologous recombination
pubmed:19779458
GO:0006303
double-strand break repair via nonhomologous end joining
pubmed:19779458
GO:0007131
reciprocal meiotic recombination
pubmed:18497861
pubmed:22002603
GO:0042138
meiotic DNA double-strand break formation
pubmed:22002603
Molecular Function
X
GO ID
Term
Links
GO:0004674
protein serine/threonine kinase activity
PubMed:10550055
Other Function
X
Function
Links
Expression
+
Related Genes
X
Name
Species
Links
Tel1
Saccharomyces cerevisiae
PubMed:11430828
PubMed Central:10930457
History
X
Created On
Last Changed
2001-07-16 16:53:52
2006-07-12 10:29:43