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About
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Statistics
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FAQs
Names
X
Name
Species
Main
ENX-1
Homo sapiens, Mus musculus
False
enx1
False
EZH2
Homo sapiens, Mus musculus
True
Keywords
X
actin, histone deacetylase complex, histone methylase, homeotic gene regulation, polycomb complex, PRC2, inactive X, linker histone, polycomb group, SANT, transcription repression, set domain, growth, cancer, H3K27 methylation, ubiquitin-dependent protein degradation, genetic disease, protein methylation, Weaver syndrome, overgrowth
Location
+
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
PcG bodies
PubMed:9584197
Interphase
chromatin
with Eed on inactive X in trophoblast stem cells
PubMed:12123576
PubMed:12689588
Mitosis
chromosomal
with Eed on inactive X in trophoblast stem cells
PubMed:12123576
Interphase
cytoplasmic
PubMed:15882624
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
85.4
6.65
746
Entrez Protein:Q15910
OMIM:277590
Uniprot:Q15910
PubMed:20601953
PubMed:20601954
PubMed:20724984
PubMed:22177091
PubMed:24214728
PubMed:28229514
85.3
6.4
746
Entrez Protein:Q61188
Uniprot:Q61188
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0030041
actin filament polymerization
PubMed:15882624
GO:0030183
B-cell differentiation
PubMed:12496962
GO:0006342
chromatin silencing
PubMed:9584199
GO:0009790
embryonic development
PubMed:11390661
GO:0030097
hemopoiesis
PubMed:16293602
GO:0016571
histone methylation
PubMed:12496962
PubMed:15099518
PubMed:12900441
PubMed:12689588
pubmed: 22323599
GO:0007517
muscle development
PubMed:15520282
GO:0006479
protein methylation
pubmed:23063525
pubmed:22215809
GO:0043161
proteasomal ubiquitin-dependent protein catabolic process
pubmed:23063525
Molecular Function
X
GO ID
Term
Links
GO:0046976
histone lysine N-methyltransferase activity (H3-K27 specific)
PubMed:12689588
GO:0018024
histone-lysine N-methyltransferase activity
PubMed:15099518
GO:0016279
protein-lysine N-methyltransferase activity
pubmed:22215809
GO:0016279
protein-lysine N-methyltransferase activity
pubmed:22215809
Other Function
X
Function
Links
Expression
+
Related Genes
X
Name
Species
Links
E(Z)
Drosophila melanogaster
PubMed:9693151
Set1
Saccharomyces cerevisiae
History
+