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Names
X
Name
Species
Main
CBX4
Homo sapiens, Mus musculus
False
PC2
Homo sapiens, Mus musculus
True
NBP16
false
Keywords
X
methyl-lysine binding, sumo binding, chromodomain, histone methylation, PRC1 complex, mitotic chromosomes, polycomb group, SUMO, SUMO E3 ligase, transcription repression, dna damage response, thymus
Location
X
Location
Species
17q25.3
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
PcG bodies
with CtBP
PubMed:12679040
PubMed:17428788
PubMed:9858600
Interphase
heterochromatin
associated with pericentric heterochromatin on HSA1
PubMed:17428788
PubMed:9722603
Mitosis
heterochromatin
remains associated with pericentric heterochromatin
PubMed:9722603
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
61.2
9.47
558
Entrez Protein:NP_003646
Uniprot:O00257
60.6
9.39
551
Entrez Protein:O55187
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0006338
chromatin remodeling
PubMed:12101246
GO:0000122
negative regulation of transcription from Pol II promoter
PubMed:12679040
PubMed:9858600
GO:0019827
stem cell maintenance
pubmed: 21885019
pubmed:23362346
GO:2000773
negative regulation of cellular senescence
pubmed: 21885019
GO:0048863
stem cell differentiation
pubmed:22226355
GOIDHERE
DNA damage response, detection of DNA damage
pubmed:22402492
GO:0016925
protein sumoylation
pubmed:22402492
pubmed:24434214
GO:0048538
thymus development
pubmed:23362346
GO:0030855
epithelial cell differentiation
pubmed:26711500
Molecular Function
X
GO ID
Term
Links
GO:0019789
SUMO ligase activity
PubMed:12679040
PubMed:17018294
pubmed: 21885019
pubmed:22402492
pubmed:24434214
GO:0032183
SUMO binding
pubmed:20176810
GO:0035064
methylated histone residue binding
pubmed:21047797
Other Function
X
Function
Links
sumo E3 ligase
PubMed:12679040
Expression
X
Experiment
Detail
Links
highly expressed in the thymic epithelium
pubmed:23362346
Related Genes
X
Name
Species
Links
Pc
Drosophila melanogaster
PubMed:11250141
History
+