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Names
X
Name
Species
Main
HD4
False
HDAC4
Gallus gallus, Homo sapiens
True
histone deacetylase 4
False
Keywords
+
Location
X
Location
Species
2q37.2
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nuclear-cytoplasmic shuttling
MEF retains it in nucleus.P sends it to cytoplasm. Shuttles in myoblasts. Nuclear in myotubes.
PubMed:11486037
PubMed:11470791
PubMed:11504882
PubMed:11792813
pubmed:16221865
pubmed:18555775
Interphase
repair foci
of DNA damage after ds breaks, together with 53BP1
PubMed:12668657
Interphase
cytoplasmic
in neurons
pubmed:16221865
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
119.1
6.49
1084
Entrez Protein:NP_006028
PubMed:11486037
Uniprot:P56524
1080
Uniprot:P83038
Annotation
X
Start
End
Domain
Description
244
279
NLS
281
284
NLS
652
998
HDAC
Class II
1059
1066
NES
CRM1-mediated
Biological Process
X
GO ID
Term
Links
GO:0016575
histone deacetylation
PubMed:11486037
GO:0000122
negative regulation of transcription from Pol II promoter
PubMed:11509672
GO:0001501
skeletal development
PubMed:15537544
GOIDHERE
neuronal survival
pubmed:17646162
Molecular Function
X
GO ID
Term
Links
GO:0004407
histone deacetylase activity
PubMed:11486037
Other Function
X
Function
Links
muscle differentiation
Expression
+
Related Genes
X
Name
Species
Links
HDA1
Saccharomyces cerevisiae
History
X
Created On
Last Changed
2001-08-07 09:44:40
2004-12-09 10:19:51