histone deacetylase, Class II HDAC
Interphase
nuclear-cytoplasmic shuttling
regulated during myogenesis. When bound to 14-3-3, HDAC4 and 5 are released from MEF2.
GO:0006338
chromatin remodeling
GO:0000122
negative regulation of transcription from Pol II promoter
GO:0004407
histone deacetylase activity
KO mice show cardiac hypertrophy in response to specific stress signals
HDA1
Saccharomyces cerevisiae
2001-08-23 13:34:24
2004-10-12 15:41:49