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Names
+
Keywords
+
Location
X
Location
Species
17q21
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
nuclear-cytoplasmic shuttling
regulated during myogenesis. When bound to 14-3-3, HDAC4 and 5 are released from MEF2.
PubMed Central:11390982
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
122
5.84
1122
Entrez Protein:Q9UQL6
Uniprot:Q9UQL6
120.9
5.81
1123
Entrez Protein:Q9Z2V6
Uniprot:Q9Z2V6
Annotation
X
Start
End
Domain
Description
280
286
NLS
681
1028
HDAC
271
277
NLS
672
1019
HDAC
Class II
Biological Process
X
GO ID
Term
Links
GO:0006338
chromatin remodeling
PubMed:11509672
GO:0000122
negative regulation of transcription from Pol II promoter
PubMed:11509672
Molecular Function
X
GO ID
Term
Links
GO:0004407
histone deacetylase activity
PubMed:11509672
Other Function
X
Function
Links
KO mice show cardiac hypertrophy in response to specific stress signals
PubMed:15367668
muscle differentiation
PubMed:11509672
PubMed Central:11390982
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
HDA1
Saccharomyces cerevisiae
PubMed Central:99238449
History
X
Created On
Last Changed
2001-08-23 13:34:24
2004-10-12 15:41:49