histone deacetylase, transcription repression, Class II HDAC
Interphase
nuclear-cytoplasmic shuttling
Serum withdrawal leads to the translocation of HDAC7 from the nucleus into the cytoplasm.
Interphase
nuclear
and in mitochondrial inner membrane space (IMS). Relocates to cytoplasm on initiation of apoptosis
GO:0006338
chromatin remodeling
GO:0000122
negative regulation of transcription from Pol II promoter
GO:0033233
regulation of protein sumoylation
GO:0030578
PML body organization
GO:0004407
histone deacetylase activity
muscle differentiation. Prevents MEF2 gene activation by binding. Sequestered to cytoplasm upon induction of differentiation.
HDA1
Saccharomyces cerevisiae
2001-08-23 14:05:53
2004-10-12 14:10:15