nsd1
Homo sapiens, Mus musculus
True
acute leukemia, AML, cancer, genetic disease, histone methylase, set domain, leukaemia, leukaemia_associated translocation, mental retardation, nuclear receptor interacting, PWWP domain, PHD finger, transcription co activator, transcription corepressor, meth, H3K36me3 binding, H3K36 methylation, DNA methylation, Sotos, overgrowth
GO:0016571
histone methylation
GO:0006357
regulation of transcription from Pol II promoter
GO:0044030
regulation of DNA methylation
GO:0046975
histone lysine N-methyltransferase activity (H3-K36 specific)
GO:0018024
histone-lysine N-methyltransferase activity
GO:0035064
methylated histone residue binding
essential for early post-implantation development
haploinsufficiency in Sotos syndrome
MES4
Caenorhabditis elegans
Set2
Saccharomyces cerevisiae
2001-08-29 14:06:40
2005-08-18 13:24:37